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Functioning of a synapse

Nicotine & Muscarine

Atropine Botox Alkyl Phosphates Toxin of the Black Widow Curare
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1. Functioning of a synapse (Signal transmission between two neurons)

2:04 min.

 

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Video Description:

1. Overview synaptic cleft, axon

2. Action potential changing voltage

3. Ca++ -channels (turquoise) open

4. Exocytosis: Synaptic vesicles discharging

5. The transmitter is discharged into the synaptic cleft

6. Protein molecules (yellow) binding transmitters

7. Ion channels (brown) binding transmitters -> an ion channel opens, if sufficiently stimulated

8. K+ -ions pour into the synaptic cleft through the ion channel

9. Na+ -ions pour into the next nerve or muscle cell

10. The voltage difference causes an action potential

11. What happens to the neurotransmitters if they are discharged:

12. The bounce back and forth in the synaptic cleft...

...until the enzyme Acetylcholinesterase (violet) splits it into its parts,...

...so it can reenter the axon terminal cell and the synaptic vesicles.

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